A Cluster-based Catalytic Hydrogenation System with High Conversion and Reversible Enantioselectivity

Summary, in English

Four tetranuclear ruthenium carbonyl hydrido clusters consisting of the enantiomeric pairs [H4Ru4(CO)10{-1,2-(R/S,R/S)-bdpp}] and [H4Ru4(CO)10{1,1-(R/S,R/S)-bdpp}] containing chiral (R,R)- or (S,S)-bdpp [bdpp = (2R/S,4R/S)-2,4-bis(diphenylphosphino)pentane] have been prepared and fully characterized. These clusters catalyze asymmetric hydrogenation of tiglic acid [trans-2-methyl-2-butenoic acid] with high conversion rates (75-100%) under relatively mild reaction conditions. Enantiomeric excesses of 40-46% were observed; the predominating enantiomeric form of the hydrogenated product is dependent on the configuration of the diphosphine ligand, indicating strong chiral induction.

• Author: Pertti Homanen; Roger Persson; Matti Haukka; Tapani Pakkanen; Ebbe Nordlander
• Department/s: Department of Chemistry
• Publishing year: 2000
• Language: English
• Pages: 5568-5568
• Publication/Series: Organometallics
• Volume: 19
• Issue: 26
• Links: http://dx.doi.org/10.1021/om000367c
• Document type: Journal article
• Publisher: The American Chemical Society (ACS)
• Topic: Inorganic Chemistry
• Status: Published
• ISBN/ISSN/Other: ISSN: 1520-6041