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Ebbe Nordlander. Portrait.

Ebbe Nordlander

Professor

Ebbe Nordlander. Portrait.

Asymmetric hydrogenation of an α-unsaturated carboxylic acid catalyzed by intact chiral transition metal carbonyl clusters-diastereomeric control of enantioselectivity

Author

  • Ahmed F. Abdel-Magied
  • Yusuf Theibich
  • Amrendra K. Singh
  • Ahibur Rahaman
  • Isa Doverbratt
  • Arun K. Raha
  • Matti Haukka
  • Michael G. Richmond
  • Ebbe Nordlander

Summary, in English

Twenty clusters of the general formula [(μ-H)2Ru3(μ3-S)(CO)7(μ-P-P∗)] (P-P∗ = chiral diphosphine of the ferrocene-based Walphos or Josiphos families) have been synthesised and characterised. The clusters have been tested as catalysts for asymmetric hydrogenation of tiglic acid [trans-2-methyl-2-butenoic acid]. The observed enantioselectivities and conversion rates strongly support catalysis by intact Ru3 clusters. A catalytic mechanism involving an active Ru3 catalyst generated by CO loss from [(μ-H)2Ru3(μ3-S)(CO)7(μ-P-P∗)] has been investigated by DFT calculations.

Department/s

  • Chemical Physics
  • Centre for Analysis and Synthesis

Publishing year

2020

Language

English

Pages

4244-4256

Publication/Series

Dalton Transactions

Volume

49

Issue

14

Document type

Journal article

Publisher

Royal Society of Chemistry

Topic

  • Physical Chemistry (including Surface- and Colloid Chemistry)

Status

Published

ISBN/ISSN/Other

  • ISSN: 1477-9226